https://slavyanski.net/sb2020/story.php?title=has-been-described-for-a-number-of-bacterial-species-for-a-9 Has been described for a number of bacterial species (for a review, see reference 7). In the case of S. pyogenes, the secreted streptococcal cysteine protease SpeB was found to cleave HK directly (8). In addition, the surface-bound M protein, one of the classical virulence determinants of GAS, has been demonstrated to bind HK, followed by bradykinin generation (9, 10). Binding and assembly of cont Wed, 12 Aug 2020 19:34:20 UTC en