https://slavyanski.net/sb2020/story.php?title=rome-and-necrotizing-fasciitis-are-associated-with-high-morbidity-and-mortality-7 Rome and necrotizing fasciitis are associated with high morbidity and mortality (1). Although GAS virulence factors have been studied intensively, the mechanisms by which local infections progress to severe systemic infections are not yet fully understood. The systemic activation of host immune responses has been reported to account for several symptoms seen in septic patients, i.e., hypotension, Mon, 24 Aug 2020 02:04:18 UTC en