The Tv Guide chose the Powerpuff Girls as No. thirteen in a record of the 50 Greatest cartoon figures of all time. The Powerpuff Girls sequence debuted on November 18, 1998, and was the highest-rated premiere in Cartoon Network's record at the time. During its run, the sequence regularly scored the highest rating for an authentic series each and every week for the network across a large array of demographics-from younger children to adults.