At lower temperatures (commonly at evening), vegetation making use of CAM open their stomata, CO2 molecules diffuse into the spongy mesophyll's intracellular areas and then into the cytoplasm. In a plant using full CAM, the stomata in the leaves continue being shut through the working day to cut down evapotranspiration, but they open at evening to collect carbon dioxide (CO2) and allow for it to diffuse into the mesophyll cells.