Archaebacteria but instead was a chimera formed by fusion and integration of the genomes of an archaebacterium and a gram-negative bacterium. The available data indicate that the primary fusion event that gave rise to the ancestral eukaryotic cell was unique and that it was very probably distinct from (and preceded) the one that gave rise to mitochondria and hydrogenosomes. These results provide e
Karyotic cell nucleus and endomembrane system as per the chimeric model. The key event in the origin of the eukaryotic cell is postulated to be a symbiotic association between a gram-negative eubacterium (from the proteobacteria-1 group) and likely an "eocyte" archaebacterium. This association led to the loss of the outer membrane from the gram-negative bacterium (not shown). As the membrane of th
Archaebacteria but instead was a chimera formed by fusion and integration of the genomes of an archaebacterium and a gram-negative bacterium. The available data indicate that the primary fusion event that gave rise to the ancestral eukaryotic cell was unique and that it was very probably distinct from (and preceded) the one that gave rise to mitochondria and hydrogenosomes. These results provide e
Ents was preceded or accompanied by duplication of the genes for the chaperone proteins (Hsp70, Hsp90, DnaJ, etc.), which are necessary for protein transport and communication within the compartments. The transfer of the genome from the gram-negative eubacterium to the newly formed nucleus and an assortment and integration of genes from the two partners led to the formation of the ancestral eukary
Sp70 (Fig. 26) and Hsp90 (Fig. 31) also contain several unique sequence signatures not found in any prokaryotic homologs. These signature provides evidence that all of the eukaryotes are derived from a single ancestor and that the postulated fusion event was unique.VOL. 62,PHYLOGENY OF PROKARYOTES AND EUKARYOTEScluding amitochondriate and aplastidic cells, received major gene contributions to the
Sp70 (Fig. 26) and Hsp90 (Fig. 31) also contain several unique sequence signatures not found in any prokaryotic homologs. These signature provides evidence that all of the eukaryotes are derived from a single ancestor and that the postulated fusion event was unique.VOL. 62,PHYLOGENY OF PROKARYOTES AND EUKARYOTEScluding amitochondriate and aplastidic cells, received major gene contributions to the
Oteobacteria). The evolutionary history deduced here based on signature sequences in some of the most highly conserved protein sequences in the biota is in contrast to the rather confusing picture that seems to be emerging from other analyses of the completed bacterial genomes (21, 50, 68, 130, 143, 144, 182, 191, 255). However, as has been pointed out (50, 143, 144, 182), of the large number of s
Oteobacteria). The evolutionary history deduced here based on signature sequences in some of the most highly conserved protein sequences in the biota is in contrast to the rather confusing picture that seems to be emerging from other analyses of the completed bacterial genomes (21, 50, 68, 130, 143, 144, 182, 191, 255). However, as has been pointed out (50, 143, 144, 182), of the large number of s