The small or large intestine is indicative of pneumatosis intestinalis. This situation refers to a necrotizing enterocolitis and can be considered as an indication for urgent surgery. Conservative management is recommended initially when these criteria are absent [50]. Badgwell et al. suggested better outcomes if it was possible to delay surgery until recovery from neutropenia [51]. General suppor
For removal in patients with septic shock, without an obvious other source of infection as the absence of local signs and symptoms are notoriously insensitive in the neutropenic host. In a cohort study of neutropenic cancer patients admitted to the ICU for severe sepsis or septic shock, Legrand et al. found that routinely removing indwelling catheters early on in patients with no other detectable