From 1912 to 1914, Irène re-entered a additional orthodox discovering ecosystem at the Collège Sévigné in central Paris from 1912 to 1914 and then on to the Faculty of Science at the Sorbonne. Irène research at the Faculty of Science ended up interrupted by World War I. After the war, Irène returned to Paris to research at the Radium Institute, which had been built by her dad and mom. Professorship at the Faculty of Science.